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Murphy dislocated his thumb in last night's Magners League match against Ulster and will be out for a minimum of four weeks, while Ronan has a similar injury with an additional fracture.
He is expected to miss out for between six and eight weeks.
Munster include the Heineken Cup 22, with the exception of Murphy, in their squad for the trip to Wales and the clash with Llanelli Scarlets on Saturday.
Also excluded from the extended squad that travelled to Coventry for the Heineken Cup semi final win over Saracens is Niall Ronan who like Murphy sustaineda a thumb injury in the game last night in Ravenhill.
Munster: D Hurley, S Payne, D Howlett, I Dowling, K Lewis, B Carney, A Horgan, R Tipoki, L Mafi, P Stringer, T O'Leary, P Warwick, R O'Gara, M Horan, F Pucciariello, J Hayes, T Buckley, F Sheahan, J Flannery, D O'Callaghan, M O'Driscoll, P O'Connell, D Ryan, A Quinlan, D Wallace, D Leamy, A Foley.
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